@charset "utf-8";

/************
1. 1380px
************/

@media only screen and (max-width: 1380px) {

/******** banner *****/
#carousel-area .carousel-item{height: 400px;}
#carousel-area .carousel-item .btn, #carousel-area .carousel-item .btn:hover, #carousel-area .carousel-item .btn:focus, #carousel-area .carousel-item .btn:active{color: #fff; font-size: 18px; padding: 10px 25px;}	
#carousel-area .btn > img{width: 11px; height: 11px; top:-3px;}
#carousel-area .carousel-item .carousel-caption h1{font-size: 45px; line-height: 50px;}	
#carousel-area .carousel-item .carousel-caption h5{font-size: 35px; line-height: 45px;}
#carousel-area .carousel-item .carousel-caption h4{font-size: 21px; line-height: 28px;}	
#carousel-area .carousel-item.carousel-one .btn-common{margin-bottom: 18px;}
#carousel-area .carousel-item.carousel-two .carousel-caption figure{width: 560px; margin-bottom: 15px;}
#carousel-area .carousel-item.carousel-three .carousel-caption h1{padding-left: 0px; text-align: left;}	
#carousel-area .carousel-item.carousel-three .carousel-content:before{width: 320px; height: 300px; left: 10%; top:20%; background-size: 100%;}
#carousel-area .carousel-item.carousel-three .carousel-content:after{width: 320px; height: 300px; right: 5%; top:20%; background-size: 100%;}
#carousel-area .carousel-item.carousel-three .carousel-caption .carousel-btn3{bottom: 75px; left: 31%;}	
#carousel-area .carousel-indicators li{width: 10px; height: 10px; margin-left: 5px; margin-right: 5px;}	
.mech-info .info-group{left: 0px;}
/******** about *******/
.about-section figure .about1{display: none;}
.about-section figure .about2{display: block;}
.about-content{padding-left: 0;}
.section-title{font-size: 35px;line-height: 40px;}
.resizemargin{margin-left: calc((100% - 1120px) / 2);}


}

@media screen and (min-width: 1200px){
.container{max-width: 1170px;}
#carousel-area .carousel-item{height: 400px;}
#carousel-area .carousel-item .btn, #carousel-area .carousel-item .btn:hover, #carousel-area .carousel-item .btn:focus, #carousel-area .carousel-item .btn:active{color: #fff; font-size: 18px; padding: 10px 45px;}	
#carousel-area .btn > img{width: 11px; height: 11px; top:-3px;}
#carousel-area .carousel-item .carousel-caption h1{font-size: 45px; line-height: 50px;}	
#carousel-area .carousel-item .carousel-caption h5{font-size: 35px; line-height: 45px;}
#carousel-area .carousel-item .carousel-caption h4{font-size: 21px; line-height: 28px; }	
#carousel-area .carousel-item.carousel-one .btn-common{margin-bottom: 18px;}
#carousel-area .carousel-item.carousel-three .carousel-caption h1{padding-left: 0px; text-align: left;}	
#carousel-area .carousel-item.carousel-three .carousel-content:before{width: 320px; height: 300px; left: 10%; top:20%; background-size: 100%;}
#carousel-area .carousel-item.carousel-three .carousel-content:after{width: 320px; height: 300px; right: 5%; top:20%; background-size: 100%;}
#carousel-area .carousel-item.carousel-three .carousel-caption .carousel-btn3{bottom: 75px; left: 31%;}	
#carousel-area .carousel-indicators li{width: 10px; height: 10px; margin-left: 5px; margin-right: 5px;}	
/******** about *******/
.about-section figure .about1{display: none;}
.about-section figure .about2{display: block;}
.about-content{padding-left: 0;}
.section-title{font-size: 35px;line-height: 45px;}
 p{font-size: 16px;line-height: 22px;}

.logo{width: 140px;}
.resizemargin{margin-left: calc((100% - 1120px) / 2);}
.sticky-wrapper .site-navbar .topbar-links li {font-size: 12px;line-height: 16px;}
.sticky-wrapper .site-navbar .topbar-links li a{font-size: 12px;line-height: 16px;}
.site-navbar .site-navigation .site-menu > li{margin: 10px 0px 8px 21px;}
.site-navbar .site-navigation .site-menu > li > a{font-size: 14px; line-height: 20px;}
.site-navbar .header-section{padding: 10px 0 6px 0;}
.sticky-wrapper{height: 146px;}
.site-navbar{height: 146px;}
.site-navbar .header-section{top: -40px;}
.sticky-wrapper .shrink .logo{width: 140px;}
#carousel-area .carousel-item .carousel-caption p{font-size: 16px;line-height: 20px;}
	/*about tramadol*/
.about-container h4{font-size: 15px;line-height: 20px;}
.about-section-info p, .about-section-info ul li{font-size: 22px;line-height: 26px;}
.tramadol-benefit p{font-size: 14px; line-height: 20px;}
.tramadol-benefit img{width: 80px;}
.indication-usage ul li:before{ width: 5px;height: 5px; top: 7px;}
.indication-usage p a{font-size: 16px; line-height: 22px;}
.tramadol-content p{font-size: 16px;line-height: 20px;}
.efficacy-content p{font-size: 16px;line-height: 20px;}
.indication-usage p{font-size: 16px;line-height: 22px;}
.indication-usage ul li{font-size: 16px;line-height: 19px;}
.about-text p a{font-size: 20px;line-height: 25px;}
.mech-act-section .action-info p{font-size: 16px;line-height: 20px;}
.mech-info .info-group h5{font-size: 20px;line-height: 25px;}
.mech-info .info-group{bottom: 6px; left: 40px;}
.efficacy-content h5{font-size: 20px;line-height: 25px;}
.mech-info .info-group1 p{font-size: 10px;line-height: 14px;}
.mech-act-section .image img{object-fit:fill;}
.efficacy-info-cont p{font-size: 20px;line-height: 24px;}
.list-numbers li{font-size: 12px;line-height: 18px;}
.efficacy-info-cont h5{font-size: 18px;line-height: 22px;}
.efficacy-info{height: 255px;}
.safety-info h5{font-size: 20px;line-height: 25px;}
.safety-info p{font-size: 17px;line-height: 22px;}
.safety-info h6{font-size: 17px;line-height: 22px;}
.table-content table thead th{font-size: 16px;line-height: 20px;padding: 12px 7px;}
.content-info p{font-size: 16px;line-height: 20px;}
.para-section p{font-size: 16px;line-height: 20px;}
.arrow-list li{font-size: 16px;line-height: 20px;}
.table-content table tbody td{font-size: 14px;line-height: 18px;}
.safety-info .small-text{font-size: 10px;line-height: 15px;}
.safety .figure-content h4{font-size: 20px;line-height: 25px;}
.para-section h5{font-size: 20px;line-height: 25px;}
.table-section h5{font-size: 20px;line-height: 25px;}
.content-info h5{font-size: 20px;line-height: 25px;}
.dosage-info h5{font-size: 20px;line-height: 25px;}
.graph-info h4{font-size: 20px;line-height: 25px;}
.dosage-indi-sec h5{font-size: 20px;line-height: 25px;}
.treatment-info-box .info-item h6{font-size: 20px;line-height: 25px;}
.safety .small-text{font-size: 11px;line-height: 15px;}
.table-content table tbody td{padding: 7px 10px;}
.arrow-list li:before{top: 8px;height:5px;width: 5px;}
.table-content p{font-size: 10px;line-height: 13px;}
.table-content h6{font-size: 10px;line-height: 13px;}
.para-section p a{font-size:16px;line-height: 20px;}
.dosage-section .para-info{font-size:16px;line-height: 20px;}
.treatment-content p{font-size:16px;line-height: 20px;}
.treatment-info-box .info-item p{font-size:16px;line-height: 20px;}
.dosage-info .dosage-img-sec img{width: 580px;}
.dosage-indi-sec p{font-size: 18px;line-height: 22px;}
.references .list-numbers li{font-size: 12px;line-height: 18px;}
.list-item-sec li{font-size: 12px;line-height: 18px;}
.description p{font-size: 12px!important;line-height: 18px;}
.description .list-numbers li{font-size: 12px;line-height: 18px;}
.description .list-numbers li{font-size: 12px;line-height: 18px;}
.description p a{font-size: 12px;line-height: 18px;}
.description h5{font-size: 14px;line-height: 20px;}
.footer-list li a{font-size: 14px;line-height: 18px;}
.footer-list-item li a{font-size: 18px;line-height: 22px;}
.footer-right p{font-size: 12px;line-height: 18px;}
.footer-block p{font-size: 12px!important;line-height: 18px;}
.footer-left .footer-block{padding-left: 15px;}
.footer-left{margin-left: 0%;}
.floting-icon .modal-title{font-size: 30px;line-height: 40px;}
.about-text .modal-title{font-size: 30px;line-height: 40px;padding-bottom: 0px;}
.floting-icon .modal-para{font-size: 20px;line-height: 25px;}
.about-text .modal-body{font-size: 20px;line-height: 25px;}
.contactForm .btn-primary{font-size: 16px;line-height: 20px;width: 190px;}
.contactForm .btn-secondary{font-size: 16px;line-height: 20px;}
.about-text .modal-footer .btn-primary{font-size: 16px;line-height: 20px;}
.about-text .modal-footer .btn-secondary{font-size: 16px;line-height: 20px;}
.table-content table thead .space{padding-left: 35px}
.table-content table thead .br-bt{border-bottom: solid 1px #FFFFFF;}
.para-section h4{font-size: 20px;line-height: 25px;}
.treatment-content h5{font-size: 20px;line-height: 25px;}
.list-item-sec li:before{width: 4px; height: 4px; top: 8px;}
.description .list-numbers li::before{width: 4px; height: 4px; top: 8px;}
	/*popup container */
.Popupcontainer .modal-title{font-size: 30px;line-height: 40px;}
.Popupcontainer p{font-size: 20px;line-height: 25px;}
.Popupcontainer .btn-primary{font-size: 16px; line-height: 20px}
.Popupcontainer .btn-secondary{font-size: 16px; line-height: 20px}
.cookiealert .modal-title{font-size: 30px;line-height: 40px;padding-bottom: 0px;}
.cookiealert p{font-size: 20px;line-height: 25px;}
.cookiealert p span{font-size: 20px;line-height: 25px;}
.Popupcontainer .modal-content{border-radius: 10px;}
.cookiealert .modal-content{border-radius: 10px;}
.cookiealert .btn {font-size: 16px; line-height: 20px}
.cookie-preferences-link .card-header h5 {padding-bottom: 0px;font-size: 20px!important;line-height: 25px!important;}
.cookie-preferences-link .card-header h5 .active_icon{font-size: 20px;line-height: 25px;}
.cookie-preferences-link .card-body {background: #EDEDED;font-size: 20px;line-height: 25px;}
.cookie-preferences-link .modal-body h5{font-size: 30px;line-height: 40px;}
.cookie-preferences-link .modal-body h5 span{font-size: 16px;line-height: 19px;}
.cookie-preferences-link .modal-body p{font-size: 20px;line-height: 25px;}
.cookie-preferences-link .modal-body button{font-size: 16px;}
.footer-right .modal-title{font-size: 30px;line-height: 40px;}
.contact-info p {font-size: 14px;line-height: 18px;}
.contact-info p a{font-size: 14px;line-height: 18px;}
.mech-info h5{font-size: 20px;line-height: 25px;}
	
}

@media only screen and (min-width: 1920px){
.container { max-width: 1640px;}
.mech-act-section .image img { object-fit: contain;}
.resizemargin {margin-left: calc((100% - 1600px) / 2);}
.section-title{font-size: 50px;line-height: 60px;}

	
/*=====================================
2. Header
====================================-*/

.site-navbar .header-section, .site-navbar .top-header, .site-navbar .top-header.hide, .logo, .sticky-wrapper, .sticky-wrapper .shrink, .sticky-wrapper .shrink .header-section, .sticky-wrapper .shrink .logo, .site-navbar .site-navigation .site-menu, .site-navbar .site-navigation .site-menu > li, .sticky-wrapper .site-navbar .topbar-links, .sticky-wrapper .shrink .site-navbar .topbar-links, .site-navbar .toggle-button .site-menu-toggle, .site-navbar.shrink .toggle-button .site-menu-toggle, .sticky-wrapper.is-sticky{webkit-transition: all 0.3s ease; -moz-transition: all 0.3s ease; -o-transition: all 0.3s ease; transition: all 0.3s ease;}
.site-navbar .top-heade{height: 110px;}
.site-navbar .header-text{position: relative;z-index: 4;}
.isi_click{color: #000000; text-decoration: underline; cursor: pointer;}
.sticky-wrapper .site-navbar .topbar-links li a{ color: #000000; text-decoration: underline;font-size: 14px;line-height: 17px;}
.sticky-wrapper .site-navbar .topbar-links li:nth-child(2) a{padding: 6px 0px;}
.sticky-wrapper .site-navbar .topbar-links{padding:20px 0px 8px 0px;}
.sticky-wrapper .site-navbar .topbar-links li:first-child:before{ content: inherit;}
.sticky-wrapper .site-navbar .header-link li{font-size: 20px;line-height: 24px;}
.site-navbar .header-text .logo-content p{font-size: 14px;line-height: 18px;}
.site-navbar {margin-bottom: 0px;z-index: 1999;position: relative; width: 100% !important; background: #fff; height: 182px;}
.site-navbar .site-navigation.border-bottom {border-bottom: 1px solid white !important; }
.site-navbar .site-navigation .site-menu {margin-bottom: 0; }
.site-navbar .site-navigation .site-menu a {text-decoration: none !important; display: inline-block; }
	.sticky-wrapper .site-navbar .header-link li:before{top: 6px;height: 16px;}
.site-navbar .site-navigation .site-menu > li {display: inline-block; margin: 10px 0px 8px 57px; position: relative; white-space: nowrap;}
.site-navbar .site-navigation .site-menu > li > a {color: #FFFFFF; display: inline-block; text-decoration: none !important; font-size: 18px;line-height: 22px; font-weight: normal; padding: 0 8px 8px 7px; -webkit-transition: all 0.3s ease-out 0s; -moz-transition: all 0.3s ease-out 0s; -ms-transition: all 0.3s ease-out 0s; -o-transition: all 0.3s ease-out 0s; transition: all 0.3s ease-out 0s; opacity: 1;text-transform: uppercase;}
.site-navbar .site-navigation .site-menu > li:nth-child(5) a{padding-right: 0px;}
.site-navbar .site-navigation .site-menu .active, .site-navbar .site-navigation .site-menu a:hover {color: #EDD236;font-weight: 500; }
.site-navbar .site-navigation .site-menu > li > a.active::before, .site-navbar .site-navigation .site-menu > li:hover > a::before {
-webkit-transform: translate(-50%) scaleX(1);-moz-transform: translate(-50%) scaleX(1);
-ms-transform: translate(-50%) scaleX(1);
-o-transform: translate(-50%) scaleX(1);
transform: translate(-50%) scaleX(1);
}
.site-navbar .site-navigation .site-menu > li > a.active::after, .site-navbar .site-navigation .site-menu > li:hover > a::after {
display: block;
-webkit-transform: translate(-50%) scaleZ(1);
-moz-transform: translate(-50%) scaleZ(1);
-ms-transform: translate(-50%) scaleZ(1);
-o-transform: translate(-50%) scaleZ(1);
transform: translate(-50%) scaleZ(1);}
.site-navbar .site-navigation .site-menu > li:first-child{ margin-left: 0px;}
.site-navbar .header-section{padding: 20px 0 10px 0;box-shadow: 0px 3px 6px #00000029;position: relative; z-index: 1;top: -55px;}
	.site-navbar .header-text .logo-content h4{font-size: 14px;}
.logo{ width: 181px; height: auto; float: left;}
.logo-mobile{display: none;}
.sticky-wrapper .shrink .logo{width: 181px;}
.logo-content p a{display: none;}
.site-navbar .site-navigation .site-menu > li.res-nav{display: none;}
.mobile-topper-links{display: none;}
.id-hash{font-size: 1px;line-height: 1px; display: block;}
/*----------------------------*/
/*---- mobile view -----------*/

.site-mobile-menu {width: 100%;position: fixed;right: 0;z-index: 999999;background: #fff;height: calc(100vh);-webkit-transform: translateX(110%);-mz-transform: translateX(110%);-ms-transform: translateX(110%);transform: translateZ(110%);-webkit-box-shadow: -10px 0 20px -10px rgba(0, 0, 0, 0.1);box-shadow: -10px 0 20px -10px rgba(0, 0, 0, 0.1);-webkit-transition: .3s all ease-in-out;-o-transition: .3s all ease-in-out;transition: .3s all ease-in-out; }
.offcanvas-menu .site-mobile-menu {-webkit-transform: translateX(0%);-ms-transform: translateX(0%);transform: translateX(0%); }
.sticky-wrapper {position: relative;z-index: 100;width: 100%; background: #fff;height: 184px;}
.sticky-wrapper .shrink {box-shadow: 0px 2px 15px rgba(0, 0, 0, 0.3);}

/*=====================================
3. banner
====================================-*/

#carousel-area {overflow: hidden;}
#carousel-area .carousel-item {height: 500px;}
#carousel-area .carousel-item .carousel-caption {top: 0; bottom: 0; right:0; left: 0; text-shadow: none; padding-top: 0; padding-bottom: 0; text-align: left; height: 100%;}
#carousel-area .carousel-item .carousel-caption h1{ font-size: 65px;line-height: 70px; font-weight: bold; color: #333984; text-align: left;}
#carousel-area .carousel-item .carousel-caption h5{font-size: 50px;line-height:60px; color: #333984;font-weight: 500;padding-bottom: 20px;}
#carousel-area .carousel-item .carousel-caption h4{font-size: 30px; color: #4C4B4C; line-height: 37px; padding-bottom: 40px; font-weight: normal;}
#carousel-area .carousel-item .carousel-caption p{font-size: 21px; line-height: 25px;color: #4C4B4C;padding-bottom: 33px;padding-top: 30px;}
#carousel-area .carousel-item .carousel-caption figure{margin: 0 0 1.5rem;}
#carousel-area .carousel-two .carousel-caption h4{padding:20px 0px 20px 0px;}
#carousel-area .carousel-item > img{ width: 100%; height: auto; -webkit-object-fit: cover; -moz-object-fit: cover; -ms-object-fit: cover; -o-object-fit: cover; object-fit: cover;}
#carousel-area .carousel-control {display: none; -webkit-transition: all 0.3s ease-in-out; -moz-transition: all 0.3s ease-in-out; -o-transition: all 0.3s ease-in-out; transition: all 0.3s ease-in-out;}
#carousel-area:hover .carousel-control {display: block; -webkit-transition: all 0.3s ease-in-out; -moz-transition: all 0.3s ease-in-out; -o-transition: all 0.3s ease-in-out; transition: all 0.3s ease-in-out; -webkit-animation-duration: 1s; animation-duration: 1s; -webkit-animation-fill-mode: both; animation-fill-mode: both; -webkit-animation-name: fadeIn; animation-name: fadeIn;}
#carousel-area .carousel-control-next, #carousel-area .carousel-control-prev {opacity: 1;}
#carousel-area .carousel-control-next i, #carousel-area .carousel-control-prev i {width: 48px; line-height: 48px; height: 48px; color: #fff; font-size: 24px; display: inline-block; background: #F97794; border-radius: 30px; -webkit-transition: all 0.2s linear; -moz-transition: all 0.2s linear; -o-transition: all 0.2s linear; transition: all 0.2s linear;}
#carousel-area .carousel-control-next i:hover, #carousel-area .carousel-control-prev i:hover {opacity: 0.9;}
#carousel-area .carousel-indicators {bottom: 20px; margin-bottom: 0px;}
#carousel-area .carousel-indicators li {width: 10px; height: 10px; border-radius: 5px; background: #FFFFFF; opacity: 1; margin-left: 8px; margin-right: 8px; border: solid 1px #FFFFFF;}
#carousel-area .carousel-indicators li.active{width: 20px; height: 10px;}
#carousel-area .carousel-indicators li:hover, #carousel-area .carousel-indicators li.active {background: #333984;border: solid 1px #333984;border-radius: 10px;}
#carousel-area .btn > img{position: relative; top:-4px;}
#carousel-area .carousel-item .carousel-caption h1 > sup{font-size: 40%; top: -1em;}
#carousel-area .carousel-item .btn, #carousel-area .carousel-item .btn:hover, #carousel-area .carousel-item .btn:focus, #carousel-area .carousel-item .btn:active{color: #fff; font-size: 28px; padding: 16px 56px; line-height: 31px; outline: none !important;}
#carousel-area .carousel-item .btn-common{margin-bottom: 104px;text-transform: none;}
#carousel-area .carousel-item.carousel-one .carousel-content {position: relative;}

#carousel-area .carousel-item.carousel-two .carousel-caption p{padding: 30px 0px 24px 0px;}
#carousel-area .carousel-item.carousel-two .carousel-caption{top: 15px;}
#carousel-area .carousel-item.carousel-two .carousel-caption h1{font-weight: 600;padding-bottom: 7px;}
#carousel-area .carousel-item.carousel-two .carousel-content{margin-top: -25px;}
#carousel-area .carousel-item.carousel-two .carousel-caption figure{margin-bottom: 20px; width: 697px;}
#carousel-area .carousel-item.carousel-two .carousel-caption figure > img{ width: 100%; height: 100%;}

#carousel-area .carousel-item.carousel-three .carousel-caption h1{font-size: 64px; padding-bottom: 20px;color: #FFFFFF;}
#carousel-area .carousel-item.carousel-three .carousel-caption h4{padding-bottom: 40px;color: #FFFFFF;}
#carousel-area .carousel-item.carousel-three .carousel-caption p{color: #FFFFFF;}
#carousel-area .carousel-item.carousel-three .carousel-content{text-align: left;}
#carousel-area .carousel-item.carousel-three .carousel-caption .carousel-btn3{position: absolute; bottom: 105px; left: 26%;}
#carousel-area .carousel-item.carousel-three .carousel-content{position: relative;}
#carousel-area .carousel-item.carousel-four .carousel-caption h1 {color: #333984;font-weight: 600; padding-bottom: 14px;}
#carousel-area .carousel-item.carousel-four .carousel-caption h4 {padding-bottom: 30px;}

#slider-area {margin-top: -1px;}
#slider-area .btn {margin-right: 15px;}
#slider-area .large_white {color: #fff;}
#slider-area .about-info p {color: #333;}

.contents p {font-size: 16px; font-weight: 400; line-height: 50px;}
.contents .header-button .btn i {margin-left: 10px;}

.small-note{font-size: 11px; line-height: 14px; color: #ffffff;}

#carousel-area .btn-effect::after {background: rgba(0, 0, 0, 0.1);}

/*============================================
================ About section =============*/
.about-content p{ font-size: 20px; line-height: 26px; color: #005392; padding-bottom: 30px;}
.about-content p > span{ font-weight: 600;}
.arrow-list li{ font-size: 24px; line-height: 29px; color: #4C4B4C; position: relative; padding-bottom: 30px; padding-left: 20px;}
.arrow-list li:before{content: ''; position: absolute; width: 8px; height: 8px; background: #333984; border-radius: 50%; left: 0px; top:12px;}
.arrow-list li:last-child{padding-bottom: 0px;}
.arrow-list li > sup{font-size: 65%;}
.arrow-list li span{text-decoration: underline;}
.about-content .btn{margin: 45px 0 20px 0; padding: 17px 40px 17px 25px}
.about-content .btn >img{position: relative; top:-2px; right:-10px;}
.about-content .small-text{ font-size: 12px; line-height: 16px; color: #58595b; padding-bottom: 0px;}

.about-container{background: #cccde0;border-radius: 30px 30px 0px 0px; padding: 30px 36px;}
.about-container h4{font-size: 22px; line-height: 27px;font-weight: 500;color: #333984;}
.about-text {background: #fff; border: 1px solid #cccde0; border-radius: 0px 0px 30px 30px;}
.about-text p{padding: 20px 36px 27px 36px;text-align: center;font-size: 30px;line-height: 37px; }
.about-text p a{font-size: 25px;line-height: 30px; color: #4C4B4C;text-decoration: underline!important;text-align: center;font-weight: 400;cursor: pointer;}
.about-text .modal-title{font-size: 40px; line-height: 45px; position: relative; color: #333984; padding-bottom: 22px;font-weight: 500;}
.about-text .modal-body{font-size: 23px; line-height: 29px; color: #4C4B4C; padding-bottom: 30px;}
.about-text .modal-header{border: 0px;}
.about-text .modal-footer{border: 0px;}
.about-text .modal-content{border-radius: 10px;border: 0px;}
.about-text .modal-footer .btn-primary{font-size: 20px;line-height: 25px;border: solid 1px #333984;background: #333984; color: #FFFFFF;padding: 14px 25px;text-transform: uppercase;}
.about-text .modal-footer .btn-secondary{font-size: 20px;line-height: 25px;border: solid 1px #333984;background: transparent; color: #333984;}


/*============================================
================== About Tramadol Section ==================*/
.about-tramadol{background: #f3f3f8; padding: 60px 0px 50px 0px;}
.tramadol-content p{font-size: 24px; line-height: 29px; color: #4C4B4C;font-weight: 400;padding-bottom: 30px}
.tramadol-content h4{font-size: 30px; line-height: 36px; color: #4C4B4C;font-weight: 500;padding-bottom: 30px;}
.tramadol-benefit p{padding: 20px 0px 40px 0px;;font-size: 24px; line-height: 30px;color: #4C4B4C;}
.indication-usage p{font-size: 24px; line-height: 30px; color: #4C4B4C;padding-bottom: 20px; }
.indication-usage .txt-underline{text-decoration: underline;}
.indication-usage ul{padding-bottom: 10px;}
.indication-usage ul li{font-size: 24px; line-height: 30px; color: #4C4B4C;position: relative;}
.indication-usage ul li:before {content: ''; position: absolute; width: 8px; height: 8px; background: #4C4B4C; border-radius: 50%; left: 0px;top: 13px;}
.indication-usage p a{color: #333984;text-decoration: underline;font-size: 24px; line-height: 30px;font-weight: bold;}


/* ==========================================================================
  Efficacy Section
   ========================================================================== */
.efficacy-content p{font-size: 24px; line-height: 29px; color: #4C4B4C; padding-bottom: 30px;}
.efficacy-content h5{font-size: 30px;line-height: 36px; color: #4C4B4C;font-weight: 500;padding-bottom: 30px;}
.efficacy-info{margin-bottom: 20px;display: flex;background: #FFFFFF;height: 415px;}
.efficacy-info-cont h5{font-size: 23px; line-height: 27px; font-weight: 500;color: #4C4B4C;}
.efficacy-info-cont p{font-size: 24px;line-height: 30px; color: #4C4B4C;padding-bottom: 20px;}
.efficacy-info-cont .ltr-spc{letter-spacing: -0.4px;}
.efficacy-info-cont{padding: 24px 50px 15px 50px;flex: 1;}
.list-numbers{padding-left: 15px;  margin-bottom: 10px;}
.list-numbers li{font-size: 18px; line-height: 22px; padding-bottom: 5px; font-weight: 400; color: #4C4B4C; list-style: decimal;letter-spacing: -0.4px;}

/* ==========================================================================
  Safety and Tolerability
   ========================================================================== */
.safety{padding: 60px 0px 25px 0px;}
.safety-info h5{font-size: 30px;line-height: 36px; color: #4C4B4C;font-weight: 500;padding-bottom: 30px;}
.safety-info p{font-size: 24px;line-height: 29px; color: #4C4B4C; padding-bottom: 30px;}
.safety-info h6{font-size: 24px;line-height: 29px; color: #4C4B4C; padding-bottom: 20px;}
.safety-info h6 span{font-weight: 500;}
.safety .small-text{font-size: 14px; line-height: 19px;color: #4C4B4C;}
.safety-info .small-text{font-size: 14px; line-height: 19px; color: #4C4B4C;padding: 20px 0px 28px 0px;font-family: "Open Sans", sans-serif;}
.safety .figure-content h4{font-size: 24px; line-height: 30px;color: #4C4B4C;padding-bottom: 26px;}
.safety .figure-content h4 span{font-weight: 500;}
	.mech-info h5{font-size: 24px;line-height: 30px;}
.figure-item .small-text{padding: 10px 0px 0px 0px;}
.figure-section {border: solid 1px #4C4B4C; margin-top: 40px; margin-bottom: 40px; background: #ffffff;}
.content-info{background: #ECECEC;padding: 45px 40px 32px 36px;}
.content-info h5{font-size: 30px; line-height: 36px; font-weight: 500;padding-bottom: 20px; color: #4C4B4C;}
.content-info p{font-size: 24px; line-height: 29px;padding-bottom: 20px;color: #4C4B4C;letter-spacing: -0.5px;}
.graph-info{padding: 25px 85px 25px 115px;}
.graph-info h4{font-size: 24px; line-height: 30px; color: #4C4B4C; padding-bottom: 18px;}
.graph-info h4 span{font-weight: 500;}
.para-section h5{font-size: 30px; line-height: 36px; color: #4C4B4C;padding-bottom: 20px;font-weight: 500;}
.para-section h4{font-size: 30px; line-height: 36px; color: #4C4B4C;font-weight: 500;position: relative;top: -20px;}
.para-section p{font-size: 24px; line-height: 29px; color: #4C4B4C;padding-bottom: 25px;}
.table-section h5{font-size: 24px; line-height: 29px; color: #4C4B4C;padding-bottom: 20px;}
.table-section h5 span{font-weight: 500;}
.table-content table{border:solid 1px #707070;margin-bottom: 0px;}
.table-content table thead th{background: #333984;font-size: 20px; line-height: 24px; font-weight: bold;color: #FFFFFF;padding: 9px 7px;vertical-align: middle;}
.table-content table thead .br-bt{border-bottom: solid 1px #FFFFFF;}
.table-content table thead th .space{padding-left: 35px}
.table-content table tbody td{background: #fbf6d7;font-size: 20px; line-height: 25px; color: #4C4B4C; padding: 9px 10px;text-align: center;}
.table-content table tbody tr{border-bottom: solid 1px #C1C1C1;}
.table-content table tbody tr td:first-child{padding-left: 35px;text-align: left;}
.table-content p{font-size: 12px; line-height: 15px; color: #4C4B4C;padding-top: 10px;}
.table-content h6{font-size: 14px; line-height: 17px; color: #4C4B4C;padding-top: 10px;}
.para-section .arrow-list li{padding-bottom: 20px;}
.para-section .isi-font{font-family: "Open Sans", sans-serif;padding-top: 10px;}
.para-section p a{font-size: 24px; line-height: 29px; font-weight: 700; color: #333984;text-decoration: underline;}
.para-section p span{font-weight: 700;}

/* ==========================================================================
  Dosage and Administration
   ========================================================================== */
.dosage-section{background: #fbf6d7;}
.dosage-section .section-title{padding-bottom: 20px;}
.dosage-section .para-info{font-size: 24px; line-height: 29px; color: #4C4B4C;padding-bottom: 30px;}
.dosage-info .dosage-img-sec{display: flex; border:solid 1px #707070; margin-bottom: 50px;background: #FFFFFF;}
.dosage-info h5{font-size: 30px; line-height: 36px;color: #4C4B4C;padding-bottom: 34px;font-weight: 500;}
.dosage-info .arrow-list{padding:30px 26px 12px 32px;}
.dosage-info .arrow-list li{padding-bottom: 20px;}
.dosage-indi-sec{background: #333984;border: solid 1px #707070;padding: 37px 40px; border-radius: 30px;}
.dosage-indi-sec h5{font-size: 30px; line-height: 36px; color: #FFFFFF; padding-bottom: 20px;font-weight: 500;}
.dosage-indi-sec p{font-size: 24px; line-height: 29px; color: #FFFFFF;padding-bottom: 20px;}
.dosage-indi-sec p:first-child{padding-bottom: 30px;}
.dosage-indi-sec .arrow-list{padding-top: 10px;}
.dosage-indi-sec .arrow-list li{padding-bottom: 20px;color: #FFFFFF;}
.dosage-indi-sec .arrow-list li:before{background: #FFFFFF;}
.dosage-info .dosage-img-sec img{width: 800px;}
/* ==========================================================================
 Tramadol treatment section
   ========================================================================== */
.treatment-content h5{font-size: 30px; line-height: 36px; color: #4C4B4C;padding-bottom: 30px;font-weight: 500;}
.treatment-content p{font-size: 24px; line-height: 29px; color: #4C4B4C; padding-bottom: 40px;}
.treatment-info-box {background: #FFFFFF; border: 2px solid #333984;border-radius: 20px;display: flex; align-items: flex-start;margin-bottom: 30px;}
.treatment-card .treatment-info-box:nth-child(1){padding: 26px 25px 15px 25px; }
.treatment-card .treatment-info-box:nth-child(2){padding: 26px 25px 45px 25px; }
.treatment-card .treatment-info-box:nth-child(3){padding: 26px 25px 20px 25px; }
.treatment-card .treatment-info-box:nth-child(4){padding: 26px 25px 45px 25px; }
.treatment-info-box .info-item{padding-left: 28px;}
.treatment-info-box .info-item h6{font-size: 24px; line-height: 29px; color: #333984; font-weight: 600;padding-bottom: 10px;}
.treatment-info-box .info-item p{font-size: 24px; line-height: 29px; color: #4C4B4C; font-weight: 400;padding-bottom: 10px;}

/* ==========================================================================
Mechanism of Action section
   ========================================================================== */
.mech-act-section {background: #D6D7E6; position: relative;}
.mech-act-section .image{position: absolute;top: 0;right: 0; height: 100%;}
.mech-act-section .image img{width: 100%; height: 100%; object-fit: cover;object-position: center;}
.mech-act-section .action-info {padding: 0px 30px 20px 0px;}
.mech-act-section .action-info .section-title{padding: 60px 0px 20px 0px;}
.mech-act-section .action-info p{font-size: 22px; line-height: 28px; color: #4C4B4C;padding-bottom: 20px;letter-spacing: -0.5px;}
.mech-act-section .action-info .rounded-box{border-radius: 30px; background: #333984;}
.mech-act-section .action-info .rounded-box p{color: #FFFFFF;}
.mech-info .info-group {position: absolute;bottom: 0px;width: 60%;left: 40px;}
.mech-info .info-group h5 .br-word{display: block;font-weight: 400;} 
.mech-info .info-group h5{font-size: 25px;line-height: 32px;color: #4C4B4C;}
.mech-info .info-group h5 span{font-weight: 500;}
.mech-info .info-group1{position: absolute;bottom: 5%; width: 26%; right: 4px;}
.mech-info .info-group1 p{font-size: 14px ; line-height: 17px;}
	.tablet_section p, .tablet_section ul li{font-size: 30px;line-height: 36px;}

/* ==========================================================================
  conatct
   ========================================================================== */
.contact-block{ padding: 50px 50px 100px 50px; position: relative; overflow: hidden; margin-bottom: 30px; border-radius: 25px;}
.contact-block h4{padding-bottom: 45px; padding-left: 45px;}
.block-right{text-align: right; }
.text-semi{font-weight: 600;}
.contact-block p > a{ color: #255ca3; text-decoration: none !important; font-size: 16px;}
.contact-block .phone > a{ color: #58595b; text-decoration: none !important; font-size: 16px;}
.pad-right{padding-right: 15px;}
.pad-left{padding-left: 15px;}
.block-left{text-align: left; position: relative;}
.block-left:before{content: ''; position: absolute; width:1px; height:100%; top:0px; left:-16px; background: #255ca3;}
.contact-block:before{ content: ''; position: absolute; width: 280px; height: 280px; bottom: -80px; right: -80px; background: url( "../images/conatct-bg.png") 0 0; background-repeat: no-repeat;}
.references{margin-bottom: 10px;}
.references h5{ font-size: 16px; line-height: 22px; font-weight: 700; padding-bottom: 12px; color: #3E3E3E;font-family: "Open Sans", sans-serif;}
.references .list-numbers{ padding-left: 16px; margin-bottom: 0px;font-family: "Open Sans", sans-serif;}
.references .list-numbers li{ font-size: 16px; color: #3E3E3E; word-break: break-word;font-family: "Open Sans", sans-serif;}

/*========================================================
=================== ISI content ============================*/
.isi-header h5{font-size: 16px; color: #4C4B4C; word-break: break-word;font-family: "Open Sans", sans-serif;font-weight: 700; padding:0px 0px 18px 0px;}
.isi-container .isi-box{border: solid 1px #4C4B4C;margin-bottom: 30px;}
.isi-container .isi-box h5{font-size: 16px; color: #4C4B4C; word-break: break-word;font-family: "Open Sans", sans-serif;font-weight: 700; padding-bottom: 10px;text-align: center;padding: 0px 0px 18px 0px}
.isi-container .isi-box p{font-size: 16px; color: #4C4B4C; font-family: "Open Sans", sans-serif; padding-bottom: 18px;text-align: center;}
.list-item-sec li{ font-size: 16px; line-height: 22px; color: #4C4B4C; position: relative; font-family: "Open Sans", sans-serif;}
.list-item-sec li:before{content: ''; position: absolute; width: 5px; height: 5px; background: #4C4B4C; border-radius: 50%; left: 0px; top:10px;font-family: "Open Sans", sans-serif;}
/*.description{padding-right: 60px;}*/
.description h5{ font-size: 16px; font-weight: 700; padding-bottom: 10px;color: #4C4B4C;font-family: "Open Sans", sans-serif;text-transform: uppercase;}
.description p{padding-bottom: 12px; color: #4C4B4C; font-size: 16px!important; line-height: 22px;font-family: "Open Sans", sans-serif;}
.description p span{text-decoration: underline;}
.description p a{text-decoration: underline;font-weight: bold; color: #333984;font-size: 16px; line-height: 20px;}
.description ol {margin-bottom: 8px;}
.description .list-numbers li {font-size: 16px; line-height:22px;padding-bottom: 10px; color: #4C4B4C; font-family: "Open Sans", sans-serif;}
.description .list-numbers li span{text-decoration: underline;}
.description p.isi-last-para{line-height: 20px;}
.description p.pre-inf > a{color: #255ca3; font-size: 14px; text-decoration: underline; font-weight: 600;}
.para-blod{font-weight: 600;}
.para-blod > a{ color: #255ca3; font-size: 14px; text-decoration: underline;}
.importantLines{padding-top: 18px;}
.sticky-isi-wrapper {position: fixed;bottom: 0;height: 150px;background: #fff;left: 0;right: 0;z-index: 9; -webkit-transition:  height 4s; /* For Safari 3.1 to 6.0 */ 
transition:  height 0.5s;
-webkit-box-shadow: 0 -5px 20px 0 rgba(0,0,0,0.35);
-ms-box-shadow: 0 -5px 20px 0 rgba(0,0,0,0.35);
-moz-box-shadow: 0 -5px 20px 0 rgba(0,0,0,0.35);
-o-box-shadow: 0 -5px 20px 0 rgba(0,0,0,0.35);
box-shadow: 0 -5px 20px 0 rgba(0,0,0,0.35);
}
.sticky-isi-head .expand-isi {position: absolute;right: 0;top: 2px;bottom: 0;margin: auto;}
.sticky-isi-head { padding: 20px 0 3px 0;position: absolute; top: 0px; right: 20px; width: 120px;}
.isi-readmore{display:none;}
.isi-readmore {color: #333984;font-size: 18px; line-height: 22px; font-weight: 600;padding-right: 8px;}
h2.isi-heading, .approved-uses h2{font-size: 16px;margin: 0;line-height: 1em;}
p.sub-head {color: #00693C;line-height: 1.3em;padding: 0;margin: 3px 0;}
.approved-uses h2 {margin: 18px 0px;}
.expand-isi img {display:inline-block;vertical-align:middle; position: relative; top: -2px;} 
.sticky-isi-outer {background: #fff;width: 100%;max-width: none;position: fixed;bottom: 0;height: 150px;left: 0;right: 0; z-index: 99;padding-bottom: 0px;display: none;transition:  height 0.5s;}
.isi-readmore{display:inline;}

@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
.description ol{margin-left: 3px;}
}

/*========================================================
=================== footer ============================*/

.footer-blk{background: #EDD236;}
.footer-block p{ font-size: 14px; line-height: 17px; color: #4C4B4C;}
.footer-block p > a{font-size: 12px; color: #4C4B4C; text-decoration: none;}
.footer-block p > a:hover{color: #4C4B4C;}
.footer-list{ padding-bottom: 30px; position: relative;}
.footer-list li{ display: inline-block; position: relative; margin: 0 10px;}
.footer-list li:first-child{margin-left: 0px;}
.footer-list li a{color: #4C4B4C; font-size: 18px; line-height: 22px;text-transform: uppercase;}
.footer-list li a::before, .footer-list li a::after{content: ''; position: absolute; width: 100%; height: 1px; background: currentColor; top: 100%; left: 0; pointer-events: none;transform-origin: 100% 50%; transform: scale3d(0, 1, 1); transition: transform 0.3s;}
.footer-list li a:hover::before{transform-origin: 0% 50%;transform: scale3d(1, 1, 1);transition: transform 0.3s;}
.footer-list li:hover a{color: #FFFFFF;}
.footer-list li .isi_click_fot{ color: #4C4B4C; text-decoration: none; cursor: pointer;}
.footer-list li:last-child{padding-left: 5px; padding-right: 0px;}
.footer-list li:nth-child(5){margin-right: 0px;}
.footer-left .footer-block{padding-left: 30px;}
.footer-left .footer-block span{display: block;}
.footer-left {display: flex;align-items: center;background: #ffffff; border-radius: 20px; padding: 40px 24px;margin-left: 8%;}
.footer-right p{ font-size: 14px; line-height: 17px; color: #4C4B4C;}
.footer-right .copy-right{display: inline-block; width: 100%;}
.footer-list-item { padding-bottom: 20px; position: relative;}
.footer-list-item li{ display: inline-block; position: relative; padding: 0 16px;}
.footer-list-item li a {color: #4C4B4C; font-size: 22px; line-height: 27px;font-weight: 500;text-decoration: underline;}
.footer-list-item li:first-child{padding-left: 0px;}
/*==============================================
============ floating-icon ==================*/

.floating-point{position: absolute; top:2.8%; z-index: 9;}
.floating-point li{padding-bottom: 60px;}
.floating-point li:last-child{padding-bottom: 0px;}
.modal-open{padding-right: 0px !important;}
.modal-open .floting-icon .modal{padding-right: 0px;}
.fl-fl.hide{right:-190px; -webkit-transition: all 0.5s ease;-moz-transition: all 0.5s ease;-ms-transition: all 0.5s ease;-o-transition: all 0.5s ease;transition: all 0.5s ease;}
.fl-fl {width: 178px;height: 48px;position: fixed;right: -130px;z-index: 1000;font: normal normal 10px Arial;
-webkit-transition: all 0.5s ease;-moz-transition: all 0.5s ease;-ms-transition: all 0.5s ease;-o-transition: all 0.5s ease;transition: all 0.5s ease;-webkit-box-shadow: 0 2px 2px 0 rgba(0,0,0,0.35);box-shadow: 0 2px 2px 0 rgba(0,0,0,0.35);overflow: hidden;background: #333984; border-top-left-radius: 6px;border-bottom-left-radius: 6px; cursor: pointer;}
.fl-fl p {font-size: 14px;color: #fff;font-weight: 500;line-height: 18px;font-style: normal;padding-left: 8px;padding-top: 2px;}
.fl-fl p span{display: block;}
.fl-link {display: block;position: absolute;top: 0px;left: 0px;bottom: 0px;width: 100%;height: 100%}
.about-text .modal-dialog {}
.floting-icon .modal.show .modal-dialog{min-height: calc(100vh - 60px);display: flex; flex-direction: column;justify-content: center; overflow: auto;}
.floting-icon .modal-content{border-radius: 10px; border:0px;}
.floting-icon .modal-body{padding:30px 40px; text-align: left;}
.floting-icon .modal-title{font-size: 40px; line-height: 45px; position: relative; color: #333984; padding-bottom: 22px;font-weight: 500;}
.floting-icon .modal-para{font-size: 23px; line-height: 29px;color: #4C4B4C;padding-bottom: 30px;}
.contactForm .btn-secondary{font-size: 20px; line-height: 25px; border: solid 1px #333984;background:transparent; color: #333984;}
.contactForm .form-group{margin-bottom: 30px;}
.contactForm .btn-primary {font-size: 20px; line-height: 25px; border: solid 1px #333984;margin-right: 40px;background: #333984;width: 210px;}
.contactForm .btn:hover{background: #EDD236; color: #FFFFFF;border: solid 1px #EDD236;}
.contactForm .form-control:focus{box-shadow: none;border-color: #ced4da;}
.floting-icon .close{ opacity: 1; padding: 0;}
.floting-icon .close:not(:disabled):not(.disabled):focus, .floting-icon .close:not(:disabled):not(.disabled):hover{opacity: 1;}
.fl-video{ background: url("../images/call-back-icon.png") 0 0; background-repeat: no-repeat; width: 48px; height: 48px;}
.fl-fl:hover {right: 0;}
.fl-coverage{background: url("../images/know-more-icon.png") 0 0; background-repeat: no-repeat; width: 48px; height:48px; position: relative;}
.use-blk .fl-fl p{padding-top: 0px; /*position: relative;left: -35px;*/ width: 129px;}

.coverage-blck .fl-fl p{padding-top: 7px; width: 129px;}
.comparision-blck .fl-fl{padding: 10px 8px;}
.comparision-blck .fl-fl p{padding-top: 15px; position: relative;}
#comparison .modal-body{padding: 30px;}
.comparision-blck  .pop-content h4{padding-left: 110px;}
.pop-content{text-align: left;}
.pop-content h4{font-weight: 600; font-size: 22px; padding-bottom: 25px;}
.pop-content p{ color: #58595b; font-size: 20px; line-height: 24px; padding-bottom: 20px;}
.pop-content p.note-pop{ color: #58595b; font-size: 12px;padding-left: 130px;}
.pop-content .fig-block p{ font-size: 16px; line-height: 20px; padding-top: 20px;color: #58595b; text-align: center;padding-bottom: 0px;}
.coverage-content{padding: 30px 13% 0 13%;}
.video-link .modal-body{padding: 10px 50px 50px 50px;}

.hcp-home.modal-open{overflow-y: hidden !important;}


/************* floating-icon-responsive **************/
.floting-icon-res{display: none; visibility: hidden;}
.floating-point-res{line-height: 0px;}
.floting-icon-res li{padding-bottom: 0px; display: inline-block; cursor: pointer; width: 33.33%; height: 60px; border-right: 1px solid #ffffff;}
.floting-icon-res li:last-child{ border-right: 0px;}
.icon-flat{padding: 10px; background: #e8ae4a; display: block; width: 100%; height: 100%;}
.icon-flat{position: relative;}
.floting-icon-res  li .fl-video{margin: 0 auto; width: 40px; height: 40px;}
.floting-icon-res  li .fl-coverage, .floting-icon-res li .fl-comparision{top:0px; margin: 0 auto; width: 40px; height: 40px;}
}


/************
2. 1199px
************/

@media only screen and (max-width: 1199.98px) {

/***** navigation *****/
.site-navbar .site-navigation .site-menu > li > a{ font-size: 12px;padding: 0px 2px 0px 3px;}
.site-navbar .site-navigation .site-menu > li{ margin-left: 6px;}
.sticky-wrapper .site-navbar .header-link li{display: inline;padding: 2px 0px;}
.sticky-wrapper .site-navbar .header-link li:nth-child(2){margin: 0px 15px;}
.sticky-wrapper .site-navbar .topbar-links{padding: 22px 0px 8px 0px;}
.site-navbar .header-text .logo-content h4{padding-top: 15px;}
.resizemargin{margin-left: calc((100% - 930px) / 2);}
.mech-act-section .resizemargin{margin-left: 0px;padding: 0px 30px;}
.action-info{margin-bottom: 20px}
.about-section-info .tablet_section p,.about-section-info ul li{font-size: 22px;line-height: 26px;}
.about-section-info .section-title{padding: 0px 0px 20px 0px;}
.site-navbar .header-text .logo-content{padding: 22px 0px 16px 20px;width: 400px;}
.sticky-wrapper .site-navbar .header-link li:before{left: -10px;top: 5px;}
.tablet_section{padding: 0px}
/******** banner ******/
#carousel-area .carousel-item{height: 350px;}
#carousel-area .carousel-item .carousel-caption p{font-size: 18px;line-height: 22px;}
#carousel-area .carousel-item .carousel-caption p br{display: none;}
#carousel-area .carousel-item .carousel-caption h1{font-size: 30px; line-height: 36px;}	
#carousel-area .carousel-item .carousel-caption h4{font-size: 16px; line-height: 20px;padding-bottom: 30px;}
#carousel-area .carousel-item .carousel-caption h5{font-size: 25px; line-height: 32px;padding-bottom: 15px;}
#carousel-area .carousel-item.carousel-three .carousel-caption h4{padding-bottom:30px;}
#carousel-area .carousel-item.carousel-two .carousel-caption p{padding-right:80px;}
#carousel-area .carousel-item.carousel-two .carousel-caption h4{padding-right:140px;}
#carousel-area .carousel-item.carousel-four .carousel-caption p{padding-right:20px;}
/*#carousel-area .btn > img {width: 9px;height: 9px;top: -3px;}*/
/*#carousel-area .carousel-item .btn, #carousel-area .carousel-item .btn:hover, #carousel-area .carousel-item .btn:focus, #carousel-area .carousel-item .btn:active{font-size: 10px;}*/
#carousel-area .carousel-item.carousel-one .carousel-content {left: 8%; top: -2px;}
#carousel-area .carousel-item.carousel-two .carousel-caption figure{width: 485px;}
#carousel-area .carousel-item.carousel-three .carousel-content:before{left: 6%; top:18%;}
#carousel-area .carousel-item.carousel-three .carousel-content:after{right: -3%; top:18%;}
#carousel-area .carousel-item.carousel-three .carousel-caption .carousel-btn3{bottom: 45px;}	
#carousel-area .carousel-item.carousel-four .carousel-content{padding-left: 0px;}
/******** MECHANISM OF ACTION ******/
.mech-act-section .image{position: relative;}
.mech-act-section .image img{max-width: 100%;height: auto;object-fit: contain;}
.mech-info .info-group{position: relative;bottom: 0;width: 100%;}
.mech-info .info-group h5{font-size: 20px;line-height: 26px;}
.mech-info .info-group1{position: relative;bottom: 0px;width: 100%;right: 0px;margin-bottom: 20px;}
.mech-box-mb{display: block;}
.mech-desk-img{display: none;}
	.info-group h5{font-size: 24px;line-height: 30px;color: #4C4B4C;}
	.info-group h5 span{font-weight: 500;}
	.info-group1 p{margin-bottom: 20px;font-size: 14px;line-height: 18px;}
/****** dosage *******/
.dosage-info .dosage-img-sec{display: block;}
/****** efficacy *******/
.efficacy-info {display: block;height: auto;}
.efficacy-info-cont {padding: 24px 15px 15px 18px;}
.footer-list-item li{padding:0 10px;}
.footer-list-item li a{font-size: 16px;line-height: 20px;}
.footer-left{margin-left: 0%;padding: 30px 10px;}
/****** footer *******/
.footer-list li{margin: 0 12px; font-size: 12px; line-height: 16px;}
.footer-list li a{font-size: 12px; line-height: 16px;}
.footer-list li:last-child{padding-left: 0px;}
.footer-right p{font-size: 12px;line-height: 16px;}
.footer-block p, .footer-block p > a{font-size: 12px;}
.footer-left .footer-block{padding-left: 18px;}
	
/******** ISI *******/
	.isi-container .isi-box{padding: 16px 10px 10px 10px}

/******** floating-icon *******/
/*.fl-fl {height: 48px;}*/
	.floating-point{top:2%;}
.fl-fl p{font-size: 13px;}
.fl-coverage, .fl-comparision{top:0px;}
.use-blk .fl-fl p{left: -50px;}	
.coverage-blck .fl-fl p{position: relative; left: -2px;}
.comparision-blck .fl-fl p{padding-top: 10px; left: -10px}	
.floating-point li {padding-bottom: 67px;}
	.sm-width{max-width: 100%;flex: auto;}
	.contactForm .btn-primary{width: 200px;}
}

@media (min-width: 1025px) and (max-width: 1199px) {
}

/************
3. 1100px
************/

@media only screen and (max-width: 1024px) {
/******** common ******/	
a[href^="tel"]:link, a[href^="tel"]:visited, a[href^="tel"]:hover, a[href^="tel:"] {
pointer-events: visible;
cursor: pointer;
text-decoration: none;
}	
/*navbar*/
.sticky-wrapper .site-navbar .topbar-links{float: none;}
.logo-content h4 span{display: inline;}
.sticky-wrapper .site-navbar .topbar-links li:nth-child(2){margin: 5px 0px;}
.sticky-wrapper .site-navbar .topbar-links li:nth-child(3){margin: 0px 0px 5px 0px;display: block;}
.sticky-wrapper .site-navbar .topbar-links{padding: 18px 0px;}
.site-navbar .site-navigation .site-menu .active{color: #EDD236!important; }
.site-navbar .site-navigation .site-menu a:hover {color: #FFFFFF;}
#carousel-area .carousel-item .carousel-caption p{font-size: 16px;line-height: 20px;}
	#carousel-area .carousel-item .carousel-caption h4{font-size: 18px;line-height: 22px;}
#carousel-area .carousel-item .carousel-caption p br{display: none;}
#carousel-area .carousel-item .carousel-caption h5{font-size: 26px;line-height: 30px;}
#carousel-area .carousel-item .carousel-caption p{padding-bottom: 20px;padding-right: 70px;}
#carousel-area .carousel-two .carousel-caption p{padding-right: 80px;}
#carousel-area .carousel-item.carousel-three .carousel-caption h1{font-size: 28px;line-height: 32px;}
#carousel-area .carousel-item.carousel-three .carousel-caption h4{padding-bottom: 25px}
#carousel-area .carousel-item.carousel-four .carousel-caption h4{padding-bottom: 30px;}
#carousel-area .carousel-one{background-position: calc(50% + 50px) center!important;}
#carousel-area .carousel-two{background-position: calc(100% + 60px) center!important}
#carousel-area .carousel-three{background-position: calc(50% + 100px) center!important}
#carousel-area .carousel-four{background-position: calc(100% + 80px) center!important}
.site-navbar .header-section{top: -45px;}
.sticky-wrapper{height: 186px;}
	.graph-info{padding: 25px;}
.site-navbar{height: 186px;}
.efficacy-info { display: block; height: auto; }
.efficacy-info-cont { padding: 24px 15px 15px 18px;}
.dosage-info .dosage-img-sec{display: block;}
.mech-act-section .sm-width{max-width:100%;flex: auto;}
.mech-act-section .image{position: relative;padding: 35px 15px!important;max-width: 100%;flex: auto}
.mech-info .info-group{width: 100%;top: -20px;}
.mech-info .info-group1{position: relative;width: 100%;top: 10px;}
.mech-info .info-group h5 .br-word{display: inline;}
/* footer */
.footer-left{padding: 25px 15px;margin-left: 0%;}
.footer-left .footer-block{padding-left:20px; }
.footer-left img{width: 170px;}
.footer-list-item li{padding: 5px 10px;display: inline;}
.footer-list-item li a{font-size: 16px;line-height: 20px;}
	
.res-mb-fea{margin-bottom: 60px;}
.res-mb-fea.res-mb-fea-3{margin-bottom: 0px;}
.res-pad-blck{padding: 60px 0;}
.res-pad-top{padding-top: 60px;}

/********* about **********/
.about-content{padding-left: 0px;}

/****** dosing *****/
.administration-block {margin-top: 50px;}	
}


/************
4. 991px
************/

@media only screen and (max-width: 991.98px) {
/******** navigation *******/
.site-navbar .toggle-button {position: relative;}
.site-navbar .toggle-button .site-menu-toggle{ font-size: 30px; line-height: 42px; color: #FFFFFF;}	
.site-mobile-menu .site-mobile-menu-header {width: 100%; float: left; padding-left: 0px; padding-right: 0px; text-align:right; background: #4C4B4C;}
.site-mobile-menu .site-mobile-menu-header .site-mobile-menu-close span {font-size: 28px; display: inline-block; padding-left: 0px; padding-right: 0px; cursor: pointer; -webkit-transition: .3s all ease; -o-transition: .3s all ease; transition: .3s all ease; color: #ffffff !important; width: 50px;height: 50px;text-align: center;line-height: 46px;}
.site-mobile-menu .site-mobile-menu-header .site-mobile-menu-close span:hover {color: #005da6; }
.site-mobile-menu .site-mobile-menu-header .site-mobile-menu-logo {float: left;margin-top: 10px;margin-left: 0px; }
.site-mobile-menu .site-mobile-menu-header .site-mobile-menu-logo a {display: inline-block;text-transform: uppercase; }
.site-mobile-menu .site-mobile-menu-header .site-mobile-menu-logo a img {max-width: 70px; }
.site-mobile-menu .site-mobile-menu-header .site-mobile-menu-logo a:hover {text-decoration: none; }
.site-mobile-menu .site-mobile-menu-body {overflow-y: auto;-webkit-overflow-scrolling: touch;position: relative;padding: 0 1px 20px 0;
height: calc(100vh - 52px);background: #4C4B4C; }
.site-mobile-menu .site-nav-wrap {padding: 0;margin: 0;list-style: none;position: relative; }
.site-mobile-menu .site-nav-wrap a {padding: 15px 20px;display: block;position: relative;color: #FFFFFF; }
.site-mobile-menu .site-nav-wrap a:hover {color: #ff8b00; }
.site-mobile-menu .site-nav-wrap li {position: relative;display: block; }
.site-mobile-menu .site-nav-wrap li .nav-link.active {color: #EDD236;font-weight: bold;}
.site-mobile-menu .site-nav-wrap .arrow-collapse {position: absolute;right: 0px;top: 10px;z-index: 20;width: 36px;height: 36px;text-align: center;cursor: pointer;border-radius: 50%; }
.site-mobile-menu .site-nav-wrap .arrow-collapse:hover {background: #f8f9fa; }
.site-mobile-menu .site-nav-wrap .arrow-collapse:before {font-size: 12px;z-index: 20; content: "\f078";position: absolute;top: 50%;left: 50%;
-webkit-transform: translate(-50%, -50%) rotate(-180deg);-ms-transform: translate(-50%, -50%) rotate(-180deg);
transform: translate(-50%, -50%) rotate(-180deg);-webkit-transition: .3s all ease;-o-transition: .3s all ease;transition: .3s all ease; }
.site-mobile-menu .site-nav-wrap .arrow-collapse.collapsed:before {-webkit-transform: translate(-50%, -50%);-ms-transform: translate(-50%, -50%);
transform: translate(-50%, -50%); }
.site-mobile-menu .site-nav-wrap > li {display: block;position: relative;float: left;width: 100%; }
.site-mobile-menu .site-nav-wrap > li > a {padding-left: 20px;font-size: 18px; }
.site-mobile-menu .site-nav-wrap > li:last-child{border-bottom: 0px;}

/******* about-section-info *******/
.resizemargin{margin-left: calc((100% - 690px) / 2);margin-right: 20px;}
.about-section-info{padding: 40px 0px;}
.tablet_section{padding: 0px;}
.mech-act-section .resizemargin{padding: 0px 60px;}
/******* header *******/	
.logo-1{position: relative; left: -50px;}
.sticky-wrapper .shrink .logo-1{position: relative; left: -50px;}
.sticky-wrapper .shrink .header-section {padding: 8px 0; background: #4c4b4b;opacity: 0.6;top: -10px;}
.sticky-wrapper .site-navbar .topbar-links{display: none;}
.site-navbar .mobile-topper-links{display: block;}
.site-navbar .mobile-topper-links .topbar-links{text-align: center;display: flex;align-items: flex-start;background: #4C4B4C;padding: 20px 0px 14px 0px;}
.site-navbar .mobile-topper-links .topbar-links li a{font-size: 14px; line-height: 17px; color: #FFFFFF;text-align: left;}
.sticky-wrapper .site-navbar .topbar-links li:nth-child(2) a{padding: 0px;}
.site-navbar .mobile-topper-links .topbar-links li:nth-child(1){padding-right: 0px;}
.site-navbar .mobile-topper-links .topbar-links li:nth-child(2){padding-right: 15px;}
.site-navbar .mobile-topper-links .topbar-links li:nth-child(3){padding-right: 0px;text-align: right;margin-right: 0px;}
.site-navbar .mobile-topper-links .topbar-links li:nth-child(3) a{text-align: right;}
.logo-content p {font-size: 12px; line-height: 14px;display: block;color: #4C4B4C;text-decoration: none;font-weight: 600;padding-top: 0px;}
.site-navbar .header-text .logo-content p{padding: 0px 0px 6px 0px;}
.site-navbar .header-text .logo-content{padding: 20px 0px 6px 12px;}
.sticky-wrapper .site-navbar .header-link li:nth-child(2){margin: 0px 15px;}
.sticky-wrapper .site-navbar .header-link li{font-size: 13px;line-height: 15px;padding: 2px 0px;}
.logo-content h4{font-size: 12px; line-height: 15px;width:100%;padding: 10px 0px 0px 0px;}
.logo-content .header-link p{display: none;}
.logo-content h4 span{display: inline;}
.header-text{display: flex;align-items: flex-start;}
.logo{display: none;}
.logo-mobile{width: 140px!important;display: block;}
	.logo-mobile img{max-width: 140px!important;}
	.cookie-preferences-link .card-header h6 .active_icon{text-align: right;}
/****** banner *****/
#carousel-area .carousel-item{height: 350px;}
#carousel-area .carousel-item .carousel-caption h4 > br{display: none;}	
#carousel-area .carousel-item .carousel-caption .mb-text-white > br{display: block;}	
#carousel-area .carousel-item.carousel-one .carousel-content{left: 45px;}
#carousel-area .carousel-item.carousel-two .carousel-content{padding: 0px 70px 0px 0px;margin-top: 0;}
#carousel-area .carousel-item.carousel-three .carousel-content:before{left: 0; top:20%; width: 275px; height: 250px;}
#carousel-area .carousel-item.carousel-three .carousel-content:after{right: -3.5%; top:20%; width: 275px; height: 250px;}
#carousel-area .carousel-item.carousel-three .carousel-caption .carousel-btn3{bottom: 65px; left: 24%;}
.site-navbar .header-section{top: -12px;background: transparent;box-shadow: none;padding: 10px 0 10px 0}
.sticky-wrapper .is-sticky .header-section{background: #000000;}
.site-navbar .mobile-topper-links .topbar-links li:nth-child(4){display: none;}
.sticky-wrapper .site-navbar .topbar-links li:nth-child(2){margin-top: 0px;padding-left: 15px;}
.sticky-wrapper { height: 180px;}
.site-navbar { height: 180px;}
.efficacy-info { height: auto;}
.mech-info .info-group h5{font-size: 26px;line-height: 30px;}
.offcanvas-menu .site-mobile-menu{top: auto;}
#carousel-area .carousel-item .carousel-caption p{padding: 20px 30px 10px 0px;}
#carousel-area .carousel-item .carousel-caption h5{font-size: 22px;line-height: 26px;}
#carousel-area .carousel-item .carousel-caption h5{padding-bottom: 10px;}
#carousel-area .carousel-item.carousel-four .carousel-caption h4{padding-right: 165px;}
#carousel-area .carousel-item .btn, #carousel-area .carousel-item .btn:hover, #carousel-area .carousel-item .btn:focus, #carousel-area .carousel-item .btn:active{font-size: 14px;line-height: 18px;}
.topper-link-sec{top: -10px;position: relative;}
.para-section h4{top: 0px;padding: 15px 0px;}
.floating-point {top: 1.6%;}
#carousel-area .carousel-one{background-position:calc(50% + 150px) center!important}
#carousel-area .carousel-two{background-position:calc(100% + 100px) center!important}
#carousel-area .carousel-three{background-position:calc(50% + 130px) center!important}
#carousel-area .carousel-four{background-position:calc(100% + 125px) center!important}
.mres{-webkit-box-flex: 0; -ms-flex: 0 0 100%; flex: 0 0 100%; max-width: 100%;}	

/********* ISI section *********/
.importantLines{padding-top: 40px;}
.sticky-isi-head .expand-isi{top:-30px;}

/********* about *********/
.about-section figure{width: 450px; height: auto; margin: 0 auto 30px auto;}
	.about-tramadol .section-title .word-br{display: block;}

/******* conatct ********/
.contact-block{padding: 25px 25px 50px 25px;}

/****** footer *******/
.footer-blk{text-align: left;}
.footer-list{padding: 0 0 13px 0; float: none; margin-top: 0px;}
.footer-block p, .footer-right p, .footer-block p > a{font-size: 14px;}
.footer-block p{padding-bottom: 3px;}
.footer-list li{ display: inline-block; padding: 5px 0px; font-size: 11px; line-height: 16px;margin-left: 0px;}
.footer-list li a{font-size: 12px; line-height: 18px; text-decoration: underline;font-weight: 500;}
.footer-list li:before{display: none;}
.footer-right p, .footer-right p.align-bottom{float: none;}
.footer-right p.align-bottom{padding-bottom: 3px; padding-left: 0px;}
.footer-list li a::before, .footer-list li a::after{position: relative;}
.footer-list-item li{display: inline;padding: 5px 10px;}

/******* backtop *******/
.back-to-top.res-show{display: inline-block !important; position: absolute; right: 15px; bottom: 0px;}
.back-to-top.res-hide{display: none !important;}

/******* websiteswitch *******/
.websiteswitch.modal.show{padding-right: 0px !important;}	
.websiteswitch .modal-content{padding: 35px;}
.websiteswitch .modal-footer{display: inline-block !important; text-align: center !important;}
.websiteswitch .modal-footer > :not(:first-child){ margin-left: 0px !important; margin-right:0px !important;}
.websiteswitch .yellow-btn, .websiteswitch .yellow-btn:hover, .websiteswitch .yellow-btn:active, .websiteswitch .yellow-btn:focus{ margin-bottom: 25px;}

/******** floting-icon ********/	
.comparison-blck figure{ width: 100%; height: auto;}
.comparison-blck figure > img{width: 100%; height: 100%;}
.comparision-blck .pop-content h4{padding-left: 0px;}
.pop-content p.note-pop{padding-left: 0px;}

.floting-icon .modal-body{padding: 10px 35px 50px 35px;}
.coverage-content{padding: 0px;}
	
/****** 404 page *****/
	
.error-section p > span{display: inline;}
}
/************
10. 820px
************/
@media only screen and (max-width: 820px) {
.site-navbar .header-section{top: -12px;background: transparent;box-shadow: none;padding: 10px 0 10px 0}
.sticky-wrapper .is-sticky .header-section{background: #000000;}
.site-navbar .mobile-topper-links .topbar-links li:nth-child(4){display: none;}
.sticky-wrapper .site-navbar .topbar-links li:nth-child(2){margin-top: 0px;padding-left: 15px;}
.sticky-wrapper { height: 180px;}
.site-navbar { height: 180px;}
.efficacy-info { height: auto;}
.mech-info .info-group h5{font-size: 26px;line-height: 30px;}
.offcanvas-menu .site-mobile-menu{top: auto;box-shadow: 0px -3px 5px rgba(50, 50, 50, 0.75);-webkit-box-shadow:  0px -3px 5px rgba(50, 50, 50, 0.75);
  -moz-box-shadow:  0px -3px 5px rgba(50, 50, 50, 0.75);}
#carousel-area .carousel-item .carousel-caption p{padding: 20px 30px 10px 0px;}
#carousel-area .carousel-item .carousel-caption h5{font-size: 22px;line-height: 26px;}
#carousel-area .carousel-item .carousel-caption h5{padding-bottom: 10px;}
#carousel-area .carousel-item .carousel-four .carousel-caption h4{padding-right: 22px;}
#carousel-area .carousel-item .btn, #carousel-area .carousel-item .btn:hover, #carousel-area .carousel-item .btn:focus, #carousel-area .carousel-item .btn:active{font-size: 14px;line-height: 18px;}
.topper-link-sec{top: -10px;position: relative;}
.para-section h4{top: 0px;padding: 15px 0px;}
.floating-point {top: 1.6%;}
.cookie-preferences-link .modal-body h5{font-size: 30px;}
.mech-act-section .resizemargin{padding: 0px 60px;}
#carousel-area .carousel-one{background-position:calc(50% + 115px) center!important}
#carousel-area .carousel-two{background-position:calc(100% + 70px) center!important}
#carousel-area .carousel-three{background-position:calc(50% + 120px) center!important}
#carousel-area .carousel-four{background-position:calc(100% + 125px) center!important}
.contactForm .btn-primary{width: 190px;}
#carousel-area .carousel-two .carousel-caption h4{padding-right: 75px;}
#carousel-area .carousel-item.carousel-two .carousel-caption p{padding-right: 80px;}
}

/************
10. 768px
************/

@media only screen and (max-width: 767.98px) {

/************* common style ***********/

.res-pad-blck{padding: 50px 0;}	
.section-title{ font-size: 40px; line-height: 48px;}	
.h-55{height: 55% !important;}
.sec-pad-60{padding: 30px 0px}
p{font-size: 18px;line-height: 22px;}
.pb-90{padding-bottom: 50px;}
.mech-info .info-group1 .zoom-img{text-align: right;}
.mech-info .info-group1 .zoom-img img{width: 77px;position: relative;top: 10px;}
.zoom-img{text-align: right;display: block;}
.zoom-img img{width: 77px;position: relative;top: 0px;}

/******** header *******/
.sticky-wrapper{height: 90px !important;}
.sticky-wrapper .site-navbar .topbar-links li:before{display: none;}
.sticky-wrapper .site-navbar .topbar-links.ml-auto{ margin: 0px auto!important;}
.sticky-wrapper .site-navbar .topbar-links li:last-child > a{display: none;}
.site-navbar .header-section{padding: 8px 0px 10px 0px;z-index: auto;top: -10px;box-shadow: none;background: transparent;}
.topper-link-sec{box-shadow: 0px 3px 6px #00000029;top:-8px;position: relative;}

.logo{ width: 140px;}	
.sticky-wrapper .shrink .logo{ width: 140px;}	

.site-navbar .toggle-button .site-menu-toggle{margin-top: -3px;}
.site-navbar.shrink	.toggle-button .site-menu-toggle{margin-top: -5px;}

/******* banner *******/
#carousel-area .carousel-item .carousel-caption h1{font-size: 20px; line-height: 24px;}	
#carousel-area .carousel-indicators{bottom: 10px;}
#carousel-area .carousel-item.carousel-one .carousel-content{top:0px;}
#carousel-area .carousel-item.carousel-two #tab-and-mobile .banner2{position: relative; top:-15px;}
#carousel-area .carousel-item.carousel-two .carousel-caption figure{ margin:10px auto 10px auto;}	
#carousel-area .carousel-item.carousel-three .carousel-content:before, #carousel-area .carousel-item.carousel-three .carousel-content:after{display: none;}
#carousel-area .carousel-item.carousel-three .carousel-caption .carousel-btn3{margin-top: 15px; bottom: 0px; left: 0px; position: relative;}

/********* about ********/
.about-section figure{width: 400px;}
.about-content .container{padding-right: 20px; padding-left: 20px;}
.arrow-list li{font-size: 18px; line-height: 22px;padding-left: 28px;}
	.dosage-info .arrow-list ul{padding: 0px 10px 0px 10px;}
.arrow-list li:before{width: 6px;  height: 6px;top: 6px;left: 8px;}
.arrow-list{margin-bottom: 30px;}
.about-container h4{font-size: 18px; line-height: 22px;}
.about-text p a{font-size: 14px; line-height: 18px;}
.about-content .section-title{font-size: 32px; line-height: 40px;}
.about-text p{font-size: 12px; line-height: 15px;}
.modal-dialog{min-height: calc(100vh - 20px);}
/********* Tramadol ********/
.tramadol-content p{font-size: 18px; line-height: 22px;}
.tramadol-content h4{font-size: 20px;line-height: 24px;}
.tramadol-benefit p{font-size: 18px; line-height: 22px;padding-bottom: 30px;}
.about-tramadol{padding: 30px 0px 20px 0px}
/********* Efficacy ********/
.efficacy-content p{font-size: 18px; line-height: 22px;}
.efficacy-content h5{font-size: 20px;line-height: 24px;}
.efficacy-info{display: block;height: auto;}
.efficacy-info-cont p{padding-bottom: 10px;}
.about-text .modal-title{font-size: 30px; line-height: 35px;padding-bottom: 0;}
.about-text .modal-body{font-size: 18px; line-height: 22px;padding-bottom: 20px;}
.about-text .modal-footer .btn-primary, .about-text .modal-footer .btn-secondary{padding: 12px 16px;font-size: 16px;line-height: 22px;}
.btn, .btn-common{font-size: 16px;line-height: 22px;display: block;}
	
	
.Popupcontainer .btn-primary{width: 160px;margin:auto;padding-bottom: 20px;margin-bottom: 20px;}
.Popupcontainer .btn-secondary{margin:auto;}
.logo-content h4 span{display: inline}
.treatment-content h5{font-size: 20px;line-height: 24px;}
	.cookiealert .modal-title{font-size: 30px;line-height: 36px;}
	.cookiealert p{font-size: 18px;line-height: 22px;}
	.cookiealert .btn{font-size: 18px;}
	.cookie-preferences-link .modal-body button{margin: auto;margin-bottom: 20px!important;}
	.cookie-preferences-link .modal-body button{font-size:18px;}

/******** safety ********/
.safety-info h5{font-size: 20px; line-height: 24px;}
.safety-info p{font-size: 18px; line-height: 22px;}
.safety-info h6{font-size: 16px; line-height: 20px;}
.safety-info .small-text{font-size: 12px; line-height: 16px; font-family: "Open Sans", sans-serif;}
.safety .figure-content h4{font-size: 20px; line-height: 25px;}
.figure-content{padding-bottom: 20px;}
.content-info{padding: 20px 15px 20px 20px}
.content-info h5{font-size: 20px; line-height: 24px;}
.content-info p{font-size: 18px; line-height: 22px;}
.graph-info{padding: 10px 20px 10px 20px; }
.graph-info h4{font-size: 20px; line-height: 25px;}
.para-section h5{font-size: 20px; line-height: 24px;}
.para-section h4{font-size: 20px; line-height: 24px;top: 0px;padding-bottom: 20px;}
.para-section p{font-size: 18px; line-height: 24px;}
.para-section .arrow-list{padding-bottom: 0!important;margin-bottom: 0!important;}
.table-section h5{font-size: 20px; line-height: 25px;}
.table-content table tbody td{font-size: 12px;line-height: 15px;}
.table-content table thead th{font-size: 12px; line-height: 15px;text-align: center;}
.table-content table thead th span{display: block;}
.table-content table thead th:first-child{padding: 9px 10px;}
.table-content p{font-size: 14px; line-height: 18px;padding-top: 5px;}
.table-content h6{font-size: 14px; line-height: 18px; padding-bottom: 20px;padding-top: 5px;}
.para-section p a{font-size: 18px; line-height: 24px;}
.table-content table tbody tr td:first-child{padding-left: 10px;vertical-align: middle;padding: 9px 10px;}
.pt-aln p:before{content: '*';position: absolute;left: 14px;}
.pt-aln p{padding-left: 5px;}
/******** dosing ********/
.dosing .container{padding-right: 20px; padding-left: 20px;}
.dosing-content{padding: 25px;}
.res-mb-fea {margin-bottom: 40px;}
.res-mb-fea.res-mb-fea-3 {margin-bottom: 40px;}	
.dosage-section .para-info{font-size: 18px; line-height: 22px;}
.dosage-info h5{font-size: 20px; line-height: 24px;}
.dosage-indi-sec{margin-left: 0px;padding: 20px 15px}
.dosage-indi-sec h5{font-size: 20px; line-height: 24px;}
.dosage-indi-sec p{font-size: 18px; line-height: 22px;}
.dosage-indi-sec .arrow-list{padding-top: 0px;margin-bottom: 10px;}
.dosage-info .dosage-img-sec{display: block;}
.dosage-info .arrow-list{padding: 40px 0px 0px 0px;margin-bottom: 0px;}
.dosage-section .para-info{padding-bottom: 30px;}
.treatment-content h5{font-size: 20px;line-height: 24px;padding-bottom: 20px;}
.treatment-content p{font-size: 18px;line-height: 22px;}
/****** Treatment section *******/
.treatment-info-box{display: block}
.treatment-info-box .info-item{padding-left: 0px;}
	.treatment-info-box .info-item p{font-size: 18px;line-height: 22px;}
.treatment-info-box .info-item h6{font-size: 20px; line-height: 25px;padding-top: 15px}
.mech-info .info-group{position: relative;width: 100%;bottom: 0;}
.mech-info .info-group h5{font-size: 20px; line-height: 25px;position: relative;top: -210px;}
.mech-act-section .image img{position: relative; top: 78px;}
.mech-info .info-group1{position: relative; width: 100%;bottom: 0;}
.mech-info .info-group1 p{font-size: 12px;line-height: 15px;font-family:  "Open Sans", sans-serif;padding-top: 10px;}
.mech-act-section .action-info{padding: 0px 15px 20px 15px}
.mech-act-section .action-info p{font-size: 18px; line-height: 22px;padding-bottom: 20px;}
.mech-act-section .action-info .rounded-box{padding: 16px 22px;margin-top: 20px;}
.mech-act-section .action-info{padding:40px 0px 20px 0px;}
.mech-act-section .action-info .section-title{padding-top: 0px;}
.mech-act-section{padding-bottom: 40px;}
.mech-info{position: relative;}
.mech-act-section .image{position: relative;padding: 0px 15px!important;}

/******* contact *******/
.contact .container{padding-right: 20px; padding-left: 20px;}
.contact-block{padding: 35px 35px 80px 35px;}
.contact-block h4{padding-left: 0px; text-align: center;}
.block-right{text-align: center; padding-right: 0px; padding-bottom: 20px}
.block-left{padding-left: 0px; padding-top: 20px; text-align: center;}
.block-left::before{ width: 100%; height: 1px; left: 0px; top:0px;}


/******* Footer *******/
.footer-blk .container{padding-right: 20px; padding-left: 20px;}
.footer-blk{text-align: left;padding: 5px 0px 30px 0px;}
.footer-list{ padding: 25px 0; float: none;}
.footer-block p{padding-bottom: 5px;}
.footer-list li{display: block; font-size: 12px; line-height: 18px;padding:6px 0px;margin: 0px;}
.footer-list li a{font-size: 16px; line-height: 20px; text-decoration: none;font-weight: 400;}	
.footer-list li:before{display: none;}
	.footer-right p span{display: block;}
.footer-right p.align-bottom{padding-left: 0px; padding-bottom: 10px;}	
.footer-block p, .footer-right p, .footer-block p > a{font-size: 14px;line-height: 17px;}
.footer-right p{padding-bottom: 30px;}
.footer-block p{padding-bottom: 3px;text-align: center}
	.footer-block p span{display: block}
.footer-left{display: block;margin-left: 0px;text-align: center;padding: 50px 35px;}
.footer-left .footer-block{padding-left: 0px;padding-top: 30px;}
.footer-block p br{display: none;}
	
/******** floating-icon *******/
	
.floting-icon{display: block; position: fixed;top: 340px; right: 20px; z-index: 1025;}

	.contactForm .btn-primary{font-size: 16px;line-height: 20px; width: 180px}
	.contactForm .btn-secondary{font-size: 16px;line-height: 20px; width: 180px}
/******** ISI ********/
/*.sticky-isi-outer{display: none !important;}*/
.sticky-isi-outer{height: 132px;}
.sticky-isi-wrapper{height: 132px;}
.res-offset{margin-left: 0;}

/******* backtop *******/
.back-to-top.res-show{display: inline-block !important; position: absolute; right: 15px; bottom: -15px;}
.back-to-top.res-hide{display: none !important;}

/***** cookiealert ********/
.cookiealert .container{padding-right: 20px; padding-left: 20px;}
.cookiealert-btn{-webkit-box-pack: center !important;
-ms-flex-pack: center !important;
justify-content: center !important;}

/***** floting-icon ********/	
.floting-icon-res{display: block; visibility: visible;}

/****** floting popup design *****/
.floting-icon .modal-header{padding: 20px 10px;}	
.floting-icon .modal.show .modal-dialog{padding: 0 10px;}
.floting-icon .modal-header .close > img{width: 60%;}
.floting-icon .modal-body{padding:10px 25px 5px 25px; }	
.floting-icon .modal-title{font-size: 30px; line-height: 36px;}
.floting-icon .modal-para{font-size: 18px; line-height: 22px;}
	.Popupcontainer .modal-content{padding: 0px;}
	.cookie-preferences-link .card-header h6{font-size: 18px!important; line-height: 22px;}
	.cookie-preferences-link .card-header h6 .active_icon{font-size: 18px; line-height: 22px;text-align: right;top: 0px;}
	.cookie-preferences-link .modal-body h6 span{position: relative;top: 0px;}
	.cookie-preferences-link .card-body{font-size: 18px;line-height: 22px;}
	.cookie-preferences-link .reject-all{margin-bottom: 20px;margin-right: 0px;width: 230px}
	.Popupcontainer .modal-title{font-size: 30px;line-height: 36px;}
	.cookie-preferences-link .confirm-choices{margin-top: 20px;}
	.Popupcontainer p{font-size: 18px;line-height: 22px;}
.contactForm .btn-primary{margin-bottom: 20px;}
	.Popupcontainer .btn-primary{font-size: 18px;line-height: 22px;padding: 12px 25px}
	.cookiealert .btn{margin: auto;}
	.cookiealert .btn.declinecookies{margin-top: 20px;}
	
	
.video-promo{height: 330px;}
.video-promo .video-promo-content h3{font-size: 20px;}	

.pop-content h4{font-size: 20px;}
.pop-content p{font-size: 16px; line-height: 22px;}

.res-mb{margin-bottom: 20px;}

::-webkit-input-placeholder {font-size: 14px; color: #888;}
::-moz-placeholder { font-size: 14px;color: #888;}
:-ms-input-placeholder { font-size: 14px; color: #888;}
:-moz-placeholder { font-size: 14px;color: #888;}
	
/****** sitemap ******/
.site-list {
    padding: 0 25px;
    text-align: center;
}
	
/****** 404 page *****/
	
.error-section:before{font-size: 200px;}
.error-section h2{font-size: 32px; line-height: 40px;}
.error-section p{font-size: 16px; line-height: 22px;}

}


/************
11. 575px
************/

@media only screen and (max-width: 576px) {

/******** header ******/	
.sticky-wrapper{height: 200px !important;}
.description ol {padding-left: 2px; margin-bottom: 8px;}
/******* header ********/
.logo{width: 140px;}
.sticky-wrapper .shrink .logo{ width: 140px;}
.site-navbar .toggle-button .site-menu-toggle{line-height: 32px; margin-top: -2px;}
.site-navbar.shrink	.toggle-button .site-menu-toggle{margin-top: -3px;}
	.treatment-box{display: flex;justify-content: center;align-items: center;}
	#carousel-area .carousel-item{height: 800px;}
/********** banner *******/
#carousel-area .carousel-item .carousel-caption h1{font-size: 30px; line-height: 38px; padding-bottom: 10px;}
#carousel-area .carousel-item .carousel-caption h5{font-size: 18px; line-height: 21px; padding: 0px 65px 20px 0px;}
#carousel-area .carousel-two .btn {width: 150px;}
#carousel-area .carousel-two .carousel-caption h4 {font-size: 16px; line-height: 20px;padding: 0px 115px 22px 0px!important;}
#carousel-area .carousel-item .carousel-caption h4 {font-size: 16px; line-height: 20px;padding: 0px 50px 22px 0px;}
#carousel-area .carousel-three .carousel-caption h4{font-size: 16px; line-height: 20px;padding: 0px 90px 22px 0px!important;}
#carousel-area .carousel-three .btn {width: 250px;}
#carousel-area .carousel-four .btn {width: 250px;}
#carousel-area .carousel-item .carousel-caption {color: #FFFFFF!important;padding: 5px 0px 30px 0px;}
#carousel-area .carousel-item .carousel-two .carousel-caption {color: #4C4B4C!important;}
#carousel-area .carousel-item .carousel-four .carousel-caption{color: #FFFFFF!important;padding: 5px 0px 30px 0px;}
#carousel-area .carousel-item .carousel-caption p{font-size: 14px; line-height: 18px;padding: 0px 30px 10px 0px;}
#carousel-area .carousel-item .carousel-three .carousel-caption p{padding-top: 0!important;}
#carousel-area .carousel-four .carousel-caption p{padding-top: 0!important;}
#carousel-area .carousel-four .carousel-caption h4{padding: 0px 50px 22px 0px!important;}
	#carousel-area .carousel-item.carousel-three .carousel-content{background: transparent;}
	.site-navbar .header-text .logo-content h4{font-size: 10px;padding-top: 20px;}
	#carousel-area .carousel-item.carousel-one .carousel-content{left: 0}
	#carousel-area .carousel-item .carousel-caption h4 > br{display: block;}
	.floting-icon{top: 315px;}
	.cookiealert{padding-left: 17px;}
	.footer-blk{padding: 25px 0px 20px 0px;}
	.Popupcontainer{padding-left: 17px;}
	.cookie-preferences-link{padding: 0px 17px!important;}
	.modal-backdrop{z-index: 999;}

/*#carousel-area .carousel-item.carousel-one .btn-common {margin-bottom: 10px;}*/
#carousel-area .carousel-item.carousel-two .carousel-caption {top: 0;}
/*#carousel-area .btn > img {top: -2px; width: 8px; height: 8px;}	*/
#carousel-area .carousel-item .btn, #carousel-area .carousel-item .btn:hover, #carousel-area .carousel-item .btn:focus, #carousel-area .carousel-item .btn:active{font-size: 12px; line-height: 16px;padding: 10px 8px;}
.site-navbar .header-text .logo-content{padding: 10px 0px 6px 12px;}
.small-note {font-size: 8px; line-height: 10px;}
	.sticky-wrapper .site-navbar .header-link li{display: inline;}
	.sticky-wrapper .site-navbar .header-link li:nth-child(2){margin: 0 15px;}
	.list-item-sec li{ font-size: 14px; line-height: 20px;padding-left: 26px;}
	.description .list-numbers li{ font-size: 14px; line-height: 20px;}
	.description p a{ font-size: 14px; line-height: 20px;}
	.description p{ font-size: 14px!important; line-height: 20px;}
	.sticky-wrapper .site-navbar .header-link li:before{left: -10px;}
	.resizemargin{margin-left: 0px;}
	.tablet_section{padding: 30px 15px;}
	.txt-right{text-align: left;}
.table-content table thead th{font-size: 12px; line-height: 15px;text-align: left;}

}

/************
12. 480px
************/

@media only screen and (max-width: 480px) {

/******** header ******/	
.sticky-wrapper{height: 210px !important;}
.description ol {padding-left: 2px; margin-bottom: 8px;}
/******* header ********/
.logo{width: 140px;}
.sticky-wrapper .shrink .logo{ width: 140px;}
.site-navbar .toggle-button .site-menu-toggle{line-height: 32px; margin-top: -2px;}
.site-navbar.shrink	.toggle-button .site-menu-toggle{margin-top: -3px;}
	.treatment-box{display: flex;justify-content: center;align-items: center;}
/********** banner *******/
#carousel-area .carousel-item .carousel-caption h1{font-size: 35px; line-height: 40px; padding-bottom: 10px;}
#carousel-area .carousel-item.carousel-one .carousel-caption h4{padding-bottom: 30px; }
#carousel-area .carousel-item.carousel-three .carousel-caption h1{font-size: 35px; line-height: 40px; }
#carousel-area .carousel-item.carousel-four .carousel-caption h1{font-size: 26px; line-height: 30px; }
#carousel-area .carousel-item .carousel-caption h5{font-size: 18px; line-height: 21px; padding: 0px 65px 20px 0px;}
#carousel-area .carousel-two .btn {width: 150px;}
#carousel-area .carousel-two .carousel-caption h4 {font-size: 16px; line-height: 20px;padding: 0px 115px 22px 0px!important;}
#carousel-area .carousel-item .carousel-caption h4 {font-size: 16px; line-height: 20px;padding: 0px 50px 22px 0px;}
#carousel-area .carousel-three .carousel-caption h4{font-size: 16px; line-height: 20px;padding: 0px 90px 22px 0px!important;}
#carousel-area .carousel-three .btn {width: 250px;}
#carousel-area .carousel-four .btn {width: 250px;}
#carousel-area .carousel-item .carousel-caption {color: #FFFFFF!important;padding: 5px 0px 30px 0px;}
#carousel-area .carousel-item .carousel-two .carousel-caption {color: #4C4B4C!important;}
#carousel-area .carousel-item .carousel-four .carousel-caption{color: #FFFFFF!important;padding: 5px 0px 30px 0px;}
#carousel-area .carousel-item .carousel-caption p{font-size: 12px; line-height: 15px;padding: 0px 30px 10px 0px;}
	#carousel-area .carousel-item.carousel-two .carousel-caption p{padding-right: 70px;}
#carousel-area .carousel-item .carousel-three .carousel-caption p{padding-top: 0!important;}
#carousel-area .carousel-four .carousel-caption p{padding-top: 0!important;}
#carousel-area .carousel-four .carousel-caption h4{padding: 0px 50px 8px 0px!important;}
	#carousel-area .carousel-item.carousel-three .carousel-content{background: transparent;}
	.site-navbar .header-text .logo-content h4{font-size: 10px;padding-top: 14px;}
	#carousel-area .carousel-item.carousel-one .carousel-content{left: 0}
	#carousel-area .carousel-item .carousel-caption h4 > br{display: block;}
	.floting-icon{top: 315px;}
	.cookiealert{padding-left: 0px;}
	.footer-blk{padding: 25px 0px 20px 0px;}
	.Popupcontainer{padding-left: 0px;}
	.cookie-preferences-link{padding: 0px 17px!important;}
	.modal-backdrop{z-index: 999;}
	.txt-left{top: 0px;}

/*#carousel-area .carousel-item.carousel-one .btn-common {margin-bottom: 10px;}*/
#carousel-area .carousel-item.carousel-two .carousel-caption {top: 0;}
/*#carousel-area .btn > img {top: -2px; width: 8px; height: 8px;}	*/
#carousel-area .carousel-item .btn, #carousel-area .carousel-item .btn:hover, #carousel-area .carousel-item .btn:focus, #carousel-area .carousel-item .btn:active{font-size: 12px; line-height: 16px;padding: 10px 8px;}
.site-navbar .header-text .logo-content{padding: 10px 0px 6px 12px;}
.small-note {font-size: 8px; line-height: 10px;}
	.sticky-wrapper .site-navbar .header-link li{display: inline;}
	.sticky-wrapper .site-navbar .header-link li:nth-child(2){margin: 0 15px;}
	.list-item-sec li{ font-size: 14px; line-height: 20px;padding-left: 26px;}
	.description .list-numbers li{ font-size: 14px; line-height: 20px;}
	.description p a{ font-size: 14px; line-height: 20px;}
	.description p{ font-size: 14px!important; line-height: 20px;}
	.sticky-wrapper .site-navbar .header-link li:before{left: -10px;}
.mb-center .table-content table thead th{text-align: center;}
.table-content table thead th{font-size: 12px; line-height: 15px;text-align: left;}
/********* about ********/
.about-section figure{width: 280px;}
.about-section-info .section-title{padding-top: 30px;}
.about-content .btn, .about-content .btn:hover, .about-content .btn:focus, .about-content .btn:active{font-size: 12px; padding: 17px 26px 17px 15px;}
.about-content .btn > img{width: 11px; height: 11px; top: -2px; right: -7px;}
.resizemargin{margin-left: 0;}
.tablet_section{padding: 0 15px 18px 15px;}
.about-section-info .section-title span{display: block;}
/******** MEchanism ********/
.mech-act-section .resizemargin{padding:0px 15px;}
.about-section-info .tablet_section p, .about-section-info .tablet_section ul li{font-size: 20px;line-height: 24px;}
.about-section-info .section-title{font-size: 40px;line-height: 45px;padding-bottom: 20px;}
.efficacy-info-cont p{font-size: 18px;line-height: 22px;}
.info-group h5{font-size: 20px;line-height: 24px;}
.info-group1 p{font-size: 12px;line-height: 16px;margin-bottom: 0px;}
.d-center-mb{display: flex;justify-content: center;align-items: center;}
	.mech-act-section .action-info{padding-top: 30px;}
	.safety{padding: 65px 0px 15px 0px;}
.mech-act-section .action-info .rounded-box{margin:0px;}
	.action-info{margin-bottom: 0px;}
/******** dosing ********/
.dose-indicator figure{width: 100%;}
	.dosage-section{padding: 30px 0px 40px 0px;}
.content{padding-top: 20px;}
.content p{font-size: 13px;}
.content .number-circle{font-size: 22px; line-height: 34px; width: 35px; height: 35px;}
.number-circle::before {width: 43px; height: 43px;}
.figure-item .zoom-img img{top: -20px;}
.treatment-info-box{margin-bottom: 40px;}
	.dosage-info h5{padding-bottom: 20px}
	.dosage-info .arrow-list{padding-top: 15px;}
	.dosage-info .dosage-img-sec{margin-bottom: 20px;}
	.dosage-indi-sec{padding: 25px 15px 0px 15px;}
	.zoom-img img{top: -20px;}
	.top-0 img{top: 0px;}
	
/****** Efficiency ******/
.dsk-block{display: none;}
.mb-block{display: block;}
/****** coverage ******/
.coverage h4{font-size: 20px;}
.coverage p{font-size: 16px; line-height: 22px;}
	.indication-usage{padding: 50px 0px}
	.indication-usage ul li{padding-left: 25px;}
	.efficay{padding: 50px 0px 60px 0px;}
/****** contact *******/
.contact-block{padding: 20px 20px 50px 20px;}
	.cookiealert .modal-content{padding: 0px;}
	.cookie-preferences-link .modal-body p{font-size: 18px;line-height: 22px;}
	.cookie-preferences-link .modal-body h5{font-size: 30px;line-height: 36px;}
	.cookie-preferences-link .card-header h6 br{display: block;}
	.cookie-preferences-link .card-header h6 a{display: flex;align-items: baseline;padding-right: 0px;}
	.contact{padding: 40px 0px 30px 0px;}
	.contact-info{text-align: center;}
/****** footer  *****/
.footer-list-item li{display: block; padding: 0px 0px 8px 0px;}
.footer-list-item li:first-child{padding-bottom: 20px;}
.footer-list li a::before, .footer-list li a::after{position: relative;}
	.contactForm .btn-primary{margin: auto;margin-bottom:20px}
	.contactForm .btn-secondary{margin: auto;margin-bottom:20px}
	.figure-content{padding-bottom: 0px;}
	.txt-right{text-align: left;top: 0;padding-bottom: 10px!important;}
	/*.safety .zoom-img img{top: 25px;}*/
}

/* Rueben for banner new */
/* element with id="tab-and-mobile" added in html */
@media screen and (max-width:767.98px){
#carousel-area .carousel-item{
background: none !important;
height:465px;
}
#carousel-area .carousel-item .carousel-caption{
display:none;
}
#tab-and-mobile{
display: block !important;
}
#tab-and-mobile img{
height: auto;
width:100%
}
#carousel-area .carousel-item .carousel-caption h1{text-align: left; padding-right: 0px;}
#tab-and-mobile .carousel-content{
padding: 5% 7% 0 7% !important;
margin-top: auto;
margin-bottom: auto;
text-align: left;

}
#tab-and-mobile figure{
width: 320px !important;
}
#tab-and-mobile figure img{
width:100%;
}

#carousel-area .carousel-item.carousel-three #tab-and-mobile h1{
padding-top: 0;
}
#carousel-area .carousel-item.carousel-three #tab-and-mobile .carousel-content,  #carousel-area .carousel-item.carousel-four #tab-and-mobile .carousel-content{
position: relative;
top: 0%;
}
}

@media screen and (min-width:767.99px){
#tab-and-mobile{
display: none !important;
}
}
@media screen and (max-width:480px){
#tab-and-mobile h4,#tab-and-mobile .small-note,#tab-and-mobile figure{
display: block !important;
} 
#carousel-area .carousel-item{height:630px;}
#tab-and-mobile figure{max-width: 280px !important;margin: auto;}
}